Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28263963 | 0.98 | SLC9A1 (0.40) | SLC9A1TSHRMAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28262770 | 0.98 | SLC9A1 (0.40) | SLC9A1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL2662182 | 0.85 | SLC9A1 (0.40) | SLC9A1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL1253404 | 0.85 | EGFR (0.42) | SLC9A1TSHRMAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1504224 | 0.84 | EGFR (0.41) | SLC9A1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL2662184 | 0.83 | PARP1 (0.37) | SLC9A1MAPTALDH1A1PKMMEN1 | |
| SCHEMBL28268477 | 0.77 | EGFR (0.43) | SLC9A1MAPTALDH1A1LMNAPKM | |
| SCHEMBL6595214 | 0.76 | TSHR (0.64) | TSHRMAPTALDH1A1LMNAPKM | |
| SCHEMBL35212204 | 0.76 | TSHR (0.64) | TSHRMAPTALDH1A1LMNAPKM | |
| Hydrochloric Acid SCHEMBL28262758 | 0.75 | TSHR (0.62) | TSHRMAPTALDH1A1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484484-B | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2021-11-23 | — | — | CN | claimed |
| CN-111484484-A | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | claimed |
| CN-111484484-B | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-111484484-A | 2, 4-diaryl aminopyrimidine derivative containing aromatic heterocycle and preparation and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | disclosed |