Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532044 | 0.92 | CYP11B2 (0.48) | CYP19A1CYP11B1CYP11B2GRM2 | |
| SCHEMBL30532043 | 0.92 | CYP11B2 (0.48) | CYP19A1CYP11B1CYP11B2GRM2 | |
| SCHEMBL21559849 | 0.92 | CYP11B2 (0.48) | CYP19A1CYP11B1CYP11B2GRM2 | |
| SCHEMBL29395229 | 0.92 | CYP11B2 (0.48) | CYP19A1CYP11B1CYP11B2GRM2 | |
| SCHEMBL28437704 | 0.91 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2GRM2 | |
| SCHEMBL22609668 | 0.88 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18929557 | 0.88 | CYP11B1 (0.44) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29398982 | 0.88 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18784757 | 0.84 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18784720 | 0.84 | CYP19A1 (0.38) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527079-A | 2- [5- (imidazol-1-ylmethyl) pyridin-3-yl ] benzimidazole derivative compound and medicine comprising the same | 日本医事物理股份有限公司 | 2020-08-11 | — | — | CN | disclosed |