Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435270 | 1.00 | PPARA (0.52) | PPARAPPARGPPARDSYKALDH1A1 | |
| SCHEMBL2856553 | 0.86 | PPARA (0.51) | PPARAPPARGSYKMAPTCTSS | |
| SCHEMBL6775947 | 0.86 | PPARA (0.51) | PPARAPPARGSYKMAPTCTSS | |
| SCHEMBL28433139 | 0.85 | PPARA (0.57) | PPARAPPARGPPARDSYKALDH1A1 | |
| SCHEMBL28433137 | 0.85 | PPARA (0.57) | PPARAPPARGPPARDSYKALDH1A1 | |
| SCHEMBL8592181 | 0.85 | CTSK (0.49) | PPARAPPARGSYKMAPTCTSS | |
| SCHEMBL8592186 | 0.85 | CTSK (0.49) | PPARAPPARGSYKMAPTCTSS | |
| SCHEMBL28434918 | 0.84 | PPARA (0.56) | PPARAPPARGPPARDSYKALDH1A1 | |
| SCHEMBL28430595 | 0.84 | PPARA (0.56) | PPARAPPARGPPARDSYKALDH1A1 | |
| SCHEMBL1429859 | 0.82 | PPARA (0.54) | PPARAPPARGPPARDSYKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484543-B | Lipopeptide TLR2 agonist and medicinal composition and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-111484543-A | Lipopeptide T L R2 agonist and medicinal composition and application thereof | 复旦大学 | 2020-08-04 | — | — | CN | disclosed |