SCHEMBL28435554

SCHEMBL28435554

CCCOC1(OC(C)C)C=CC(C(=O)c2ccccc2)=C(O)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.34
CCNB2 O95067 4/20 0.34
CCNE2 O96020 4/20 0.34
CDK1 P06493 4/20 0.34
CCNB1 P14635 4/20 0.34
CCNE1 P24864 4/20 0.34
CDK2 P24941 4/20 0.34
CCNB3 Q8WWL7 4/20 0.34
ELANE P08246 2/20 0.33
PTPN1 P18031 1/20 0.32
ALDH1A1 P00352 4/20 0.32
RAB9A P51151 1/20 0.32
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28438347 0.94 ELANE (0.34) LMNACCNB2CCNE2CDK1CCNB1
SCHEMBL28438117 0.91 ELANE (0.34) LMNAHSD17B10CCNB2CCNE2CDK1
SCHEMBL28327487 0.88 ELANE (0.38) LMNAHSD17B10ELANEALDH1A1RAB9A
SCHEMBL28438096 0.87 LMNA (0.38) LMNAHSD17B10CCNB2CCNE2CDK1
SCHEMBL28435555 0.86 LMNA (0.37) LMNAHSD17B10CCNB2CCNE2CDK1
SCHEMBL28441977 0.85 ELANE (0.36) LMNAHSD17B10ELANEALDH1A1RAB9A
SCHEMBL28438104 0.84 LMNA (0.35) LMNAHSD17B10CCNB2CCNE2CDK1
SCHEMBL28694799 0.84 LMNA (0.35) LMNACCNB2CCNE2CDK1CCNB1
SCHEMBL28438094 0.82 ELANE (0.34) LMNAHSD17B10ELANEALDH1A1PTGES
SCHEMBL28436065 0.81 LMNA (0.34) LMNACCNB2CCNE2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599689-B Bleaching agent, preparation thereof and use thereof with polymerizable compositions for optical materials 三井化学株式会社 2024-05-31 CN disclosed
CN-116940867-A Method for manufacturing optical material and composition used in the method 三井化学株式会社 2023-10-24 CN disclosed
CN-114599689-A Bleaching agent, its preparation and its use with polymerizable compositions for optical materials 三井化学株式会社 2022-06-07 CN disclosed
CN-110291122-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2022-03-01 CN disclosed
CN-108350106-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2021-05-14 CN disclosed
CN-111406076-A Polymerizable composition for optical material, molded body, optical material, plastic lens, and method for producing same 三井化学株式会社 2020-07-10 CN disclosed