SCHEMBL28436330

SCHEMBL28436330

CCOC(=S)NS(=O)(=O)CC(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.39
GAA P10253 2/20 0.39
SI P14410 2/20 0.39
MGAM2 Q2M2H8 2/20 0.39
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
CA12 O43570 5/20 0.33
CA14 Q9ULX7 3/20 0.33
CA2 P00918 3/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 6/20 0.32
TRPA1 O75762 1/20 0.32
TSHR P16473 2/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.31
LMNA P02545 1/20 0.31
CYP2D6 P10635 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28434498 0.82 ALDH1A1 (0.38) MGAMGAASIMGAM2MAPT
SCHEMBL30022589 0.81 MGAM (0.33) MGAMGAASIMGAM2MAPT
SCHEMBL1101451 0.72 POLB (0.38) MGAMGAASIMGAM2MAPT
SCHEMBL15912132 0.69 TSHR (0.40) MGAMGAASIMGAM2POLB
SCHEMBL15827325 0.69 CA12 (0.43) MGAMGAASIMGAM2CA12
SCHEMBL6249700 0.68 TSHR (0.43) MGAMGAASIMGAM2CA12
SCHEMBL26876020 0.67 GAA (0.52) MGAMGAASIMGAM2KMT2A
SCHEMBL19103697 0.67 TSHR (0.39) MGAMGAASIMGAM2MAPT
SCHEMBL5718363 0.66 CA12 (0.48) MGAMGAASIMGAM2MAPT
SCHEMBL10260586 0.65 TSHR (0.48) MGAMGAASIMGAM2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511818-A Polymer substrates with attached polymer chains 3M创新有限公司 2020-08-07 CN disclosed
CN-111511817-A Polymer substrates having attached thiocarbonylthio-containing groups 3M创新有限公司 2020-08-07 CN disclosed