Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317883 | 0.86 | TDP1 (0.50) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL14378828 | 0.83 | CES2 (0.50) | ALDH1A1GAAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL27496383 | 0.82 | HPGD (0.57) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL29250 | 0.82 | HPGD (0.57) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL27352197 | 0.81 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL18073 | 0.81 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL9241160 | 0.81 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL9353455 | 0.81 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL9353461 | 0.81 | TDP1 (0.54) | MAPTALDH1A1L3MBTL1TDP1ATM | |
| SCHEMBL5237061 | 0.81 | ELANE (0.50) | MAPTALDH1A1L3MBTL1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724110-B1 | Multilayered articles and method of manufacture thereof | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-08-21 | — | — | EP | disclosed |
| US-8900693-B2 | Polycarbonate compositions having infrared absorbance, method of manufacture, and articles prepared therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2014-12-02 | — | — | US | disclosed |
| EP-1907465-B1 | POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-07-23 | — | — | EP | disclosed |
| EP-1529632-B1 | Multilayered articles and method of manufacture thereof | SABIC INNOVATIVE PLASTICS IP (NL) | 2012-09-05 | — | — | EP | disclosed |
| EP-2202063-A2 | Multilayered articles and method of manufacture thereof | Sabic Innovative Plastics IP B.V. (NL) | 2010-06-30 | — | — | EP | disclosed |
| EP-1559743-B1 | Infra-red radiation absorption articles and method of manufacturing thereof | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-02-18 | — | — | EP | disclosed |
| EP-1996650-A2 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | Sabic Innovative Plastics IP B.V. (NL) | 2008-12-03 | — | — | EP | disclosed |
| US-7399571-B2 | Multilayered articles and method of manufacture thereof | GENERAL ELECTRIC COMPANY (US) | 2008-07-15 | — | — | US | disclosed |
| EP-1907465-A2 | POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | General Electric Company (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2008013579-A2 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-01-31 | — | — | WO | disclosed |
| WO-2005087008-A2 | BIOCIDAL COMPOSITIONS AND METHODS OF MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087855-A1 | BIOCIDAL COMPOSITIONS AND METHODS OF MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050203237-A1 | Biocidal compositions and methods of making thereof | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-09-15 | — | — | US | disclosed |
| US-20050202100-A1 | Biocidal compositions and methods of making thereof | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-09-15 | — | — | US | disclosed |
| WO-2005075550-A1 | INFRA-RED RADIATION ABSORPTION ARTICLES AND METHOD OF MANUFACTURE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| EP-1559743-A1 | Infra-red radiation absorption articles and method of manufacturing thereof | GENERAL ELECTRIC COMPANY (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20050165148-A1 | Infra-red radiation absorption articles and method of manufacture thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2005-07-28 | — | — | US | disclosed |
| WO-2005053953-A1 | MULTIWALL SHEETS AND METHODS FOR MANUFACTURING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
| US-20050112331-A1 | Multiwall sheets and methods for manufacturing thereof | GENERAL ELECTRIC COMPANY | 2005-05-26 | — | — | US | disclosed |
| EP-1529632-A1 | Multilayered articles and method of manufacture thereof | GENERAL ELECTRIC COMPANY (US) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050202100-A1 | Biocidal compositions and methods of making thereof | PIK3C3, PRKACG, PRKX | MAPT 2975/4885ALDH1A1 695/4885L3MBTL1 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.