Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349903 | 0.73 | CYP11B1 (0.42) | CYP11B1CYP11B2S1PR1ALDH1A1RAB9A | |
| SCHEMBL987523 | 0.70 | CYP11B1 (0.49) | CYP11B1CYP11B2S1PR1ALDH1A1RAB9A | |
| SCHEMBL22576217 | 0.70 | ALDH1A1 (0.55) | MBOAT4ADORA2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7970286 | 0.67 | KMT2A (0.43) | MBOAT4SLC6A3ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL12531530 | 0.67 | CYP11B1 (0.49) | CYP11B1CYP11B2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL988896 | 0.67 | CYP11B1 (0.49) | CYP11B1CYP11B2S1PR1ALDH1A1RAB9A | |
| SCHEMBL6449446 | 0.65 | HRH3 (0.58) | CYP11B1CYP11B2 | |
| SCHEMBL28438099 | 0.65 | SLC6A4 (0.46) | MBOAT4MAOAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL196775 | 0.64 | CYP1A2 (0.44) | CYP11B1CYP11B2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL14468248 | 0.63 | CYP11B1 (0.45) | CYP11B1CYP11B2ADORA2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518022-A | Aromatic (hetero) cyclic ether compound with insecticidal activity and preparation method and application thereof | 华东理工大学 | 2020-08-11 | — | — | CN | disclosed |