SCHEMBL28438415

SCHEMBL28438415

CCOCO[Si](CCCOCC1CO1)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25906825 0.91 TSHR (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL283698 0.90 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1360905 0.87 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL29150940 0.86 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1920460 0.85 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL3446854 0.85 TSHR (0.55) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064005 0.85 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28449500 0.85 TSHR (0.58) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28441440 0.85 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL284717 0.85 TSHR (0.61) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715989-B Hose, abrasion resistant composition and hose manufacturing process 库博标准汽车配件有限公司 2020-08-14 CN disclosed