SCHEMBL6064005

SCHEMBL6064005

CCCO[Si](CCCOCC1CO1)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.57
ALDH1A1 P00352 5/20 0.54
TDP1 Q9NUW8 1/20 0.54
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.35
PDK1 Q15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064602 0.97 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064293 0.95 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064488 0.93 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6063435 0.93 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188109 0.92 SMN1; SMN2 (0.62) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28449500 0.91 TSHR (0.58) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL27484693 0.90 ALDH1A1 (0.61) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL283698 0.89 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064397 0.89 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL6064312 0.88 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114410138-A Inorganic waterproof flame-retardant coating and preparation method thereof 广州昊特建材有限公司 2022-04-29 CN disclosed
US-7141306-B1 Sol-gel composition and process for coating aerospace alloys CESSNA AIRCRAFT COMPANY (US) 2006-11-28 US disclosed