Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 12/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436519 | 0.89 | RET (0.41) | RETRAF1CKS1BSKP1SKP2 | |
| SCHEMBL30111209 | 0.80 | RET (0.47) | RETRAF1GPR119CKS1BSKP1 | |
| SCHEMBL24879320 | 0.80 | RET (0.47) | RETRAF1GPR119CKS1BSKP1 | |
| SCHEMBL23647637 | 0.79 | RET (0.49) | RETGPR119 | |
| SCHEMBL30511931 | 0.79 | RET (0.45) | RETRAF1CKS1BSKP1SKP2 | |
| SCHEMBL19785238 | 0.79 | RET (0.45) | RETRAF1CKS1BSKP1SKP2 | |
| SCHEMBL22791979 | 0.78 | RET (0.41) | RETRAF1CKS1BSKP1SKP2 | |
| SCHEMBL30453246 | 0.78 | RET (0.37) | RETRAF1KIF18AGPR119 | |
| SCHEMBL23657205 | 0.78 | RET (0.47) | RETRAF1GPR119 | |
| SCHEMBL29770946 | 0.78 | RET (0.47) | RETRAF1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-111484479-A | Nitrogen heterocyclic compound, pharmaceutical composition containing nitrogen heterocyclic compound, preparation method and application of nitrogen heterocyclic compound | 四川科伦博泰生物医药股份有限公司 | 2020-08-04 | — | — | CN | disclosed |