Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441623 | 0.85 | KMT2A (0.53) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL28442196 | 0.82 | PTK2 (0.49) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL9129364 | 0.81 | EGFR (0.47) | LMNAKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27464722 | 0.76 | KMT2A (0.60) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL10500172 | 0.76 | KMT2A (0.58) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL28444754 | 0.75 | LMNA (0.51) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL28462916 | 0.74 | KMT2A (0.59) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL16685068 | 0.74 | KMT2A (0.77) | LMNAKMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL9693934 | 0.74 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL27989385 | 0.74 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111394747-B | Green electrochemical synthesis method of 2-acyloxy aniline derivatives | 浙江工业大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-111394747-A | Green electrochemical synthesis method of 2-acyloxy aniline derivatives | 浙江工业大学 | 2020-07-10 | — | — | CN | disclosed |