Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445183 | 0.90 | TAAR1 (0.54) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL28434556 | 0.85 | TAAR1 (0.53) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL28442721 | 0.84 | FGFR4 (0.58) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL22860800 | 0.82 | JAK2 (0.59) | — | |
| SCHEMBL28896995 | 0.79 | JAK2 (0.57) | TAAR1SLC6A3 | |
| SCHEMBL28445172 | 0.79 | JAK2 (0.46) | — | |
| SCHEMBL28439364 | 0.79 | JAK2 (0.54) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL28442728 | 0.78 | JAK2 (0.67) | TAAR1SLC6A3 | |
| SCHEMBL28451446 | 0.78 | JAK2 (0.53) | — | |
| SCHEMBL28447921 | 0.78 | JAK2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423384-B | 2-aminopyrimidine compounds and application thereof | 沈阳药科大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-111423384-A | 2-aminopyrimidine compounds and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | disclosed |