Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332971 | 0.77 | MAPT (0.48) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16719426 | 0.76 | MAOB (0.49) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3251181 | 0.76 | CYP1A2 (0.43) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4085854 | 0.76 | TSHR (0.53) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18586527 | 0.76 | MAPT (0.45) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11115046 | 0.76 | POLB (0.41) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12100932 | 0.76 | HTR1A (0.44) | MAPTNPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15009036 | 0.76 | APP (0.57) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL16719452 | 0.75 | NPC1 (0.43) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL943714 | 0.75 | POLB (0.40) | MAPTNPSR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |