Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.75 |
| ▸ | AXL | P30530 | 9/20 | 0.75 |
| ▸ | KDR | P35968 | 8/20 | 0.75 |
| ▸ | RET | P07949 | 3/20 | 0.75 |
| ▸ | KIT | P10721 | 3/20 | 0.75 |
| ▸ | FLT3 | P36888 | 3/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.75 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.75 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.71 |
| ▸ | MERTK | Q12866 | 6/20 | 0.68 |
| ▸ | AURKA | O14965 | 2/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.66 |
| ▸ | ABL1 | P00519 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 2/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.66 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.66 |
| ▸ | LCK | P06239 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21273499 | 0.99 | MET (0.76) | METAXLKDRRETKIT | |
| SCHEMBL28446145 | 0.98 | MET (0.75) | METAXLKDRRETKIT | |
| Ammonia Solution, Strong SCHEMBL28433460 | 0.98 | MET (0.75) | METAXLKDRRETKIT | |
| Ammonia Solution, Strong SCHEMBL21273442 | 0.98 | MET (0.75) | METAXLKDRRETKIT | |
| SCHEMBL28436306 | 0.98 | MET (0.75) | METAXLKDRRETKIT | |
| SCHEMBL21273541 | 0.98 | MET (0.75) | METAXLKDRRETKIT | |
| SCHEMBL21273569 | 0.98 | MET (0.75) | METAXLKDRRETKIT | |
| SCHEMBL28446147 | 0.98 | HDAC2 (0.74) | METAXLKDRRETKIT | |
| SCHEMBL28434334 | 0.97 | HDAC2 (0.76) | METAXLKDRRETKIT | |
| SCHEMBL28444393 | 0.97 | HDAC2 (0.76) | METAXLKDRRETKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109496212-B | Quinolyl-substituted carboxylic acid compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition and application thereof | 北京康辰药业股份有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-109496212-B | Quinolyl-substituted carboxylic acid compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition and application thereof | 北京康辰药业股份有限公司 | 2020-08-14 | — | — | CN | disclosed |