Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091599 | 0.85 | NR1H4 (0.47) | HPGDERN1 | |
| SCHEMBL9249047 | 0.80 | UNG (0.50) | UNGRAB9ANPC1CA12CA1 | |
| SCHEMBL9244583 | 0.77 | UNG (0.47) | UNGCA12CA1CA2CA6 | |
| SCHEMBL29069395 | 0.77 | POLB (0.36) | UNGRAB9ANPC1MITFMAPT | |
| Putrescine SCHEMBL9421032 | 0.71 | UNG (0.43) | UNGCA12CA1CA2CA6 | |
| SCHEMBL6929322 | 0.71 | NR4A2 (0.45) | RAB9ANPC1SMN1; SMN2CYP1A2HPGD | |
| SCHEMBL28446737 | 0.70 | KDM4E (0.47) | UNGRAB9ANPC1MITFMAPT | |
| SCHEMBL7610841 | 0.70 | KMO (0.45) | UNGKMOERN1 | |
| SCHEMBL1574454 | 0.70 | UNG (0.50) | UNGRAB9ANPC1MAPTCA12 | |
| SCHEMBL27788893 | 0.70 | UNG (0.50) | UNGCA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627767-B | Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and application thereof | 中国药科大学 | 2020-08-25 | — | — | CN | disclosed |