Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220358 | 0.89 | POLB (0.60) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL6855776 | 0.82 | ALDH1A1 (0.65) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL6850954 | 0.81 | ALDH1A1 (0.71) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL28440302 | 0.80 | NPC1 (0.62) | POLBTDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28440244 | 0.79 | NPC1 (0.47) | KMT2AALDH1A1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL13696936 | 0.77 | POLB (0.60) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL10060206 | 0.77 | POLB (0.60) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL8477021 | 0.76 | POLB (0.63) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL10895321 | 0.76 | POLB (0.62) | POLBCASP6TDP1KMT2AALDH1A1 | |
| SCHEMBL13923626 | 0.76 | SMN1; SMN2 (0.68) | POLBKMT2AALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533707-B | Preparation method of polysubstituted oxazole-2 (3H) -ketone compound | 中国科学院长春应用化学研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-111533707-A | Preparation method of polysubstituted oxazole-2 (3H) -ketone compound | 中国科学院长春应用化学研究所 | 2020-08-14 | — | — | CN | disclosed |