Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450751 | 0.87 | POLB (0.35) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL28441986 | 0.81 | POLB (0.31) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL28436164 | 0.80 | MAPT (0.45) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL28434738 | 0.79 | ALDH1A1 (0.39) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL22492486 | 0.78 | MAPT (0.37) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL22492511 | 0.71 | MAPT (0.44) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL22492599 | 0.70 | MAPT (0.36) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL26247863 | 0.67 | MAPT (0.46) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL26247861 | 0.67 | MAPT (0.46) | POLBALDH1A1MCOLN3HTTMAPT | |
| SCHEMBL22492463 | 0.67 | MAPT (0.43) | POLBALDH1A1MCOLN3HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417620-A | Creatine prodrugs, compositions thereof, and methods of use | 奥特吉尼克斯制药公司 | 2020-07-14 | — | — | CN | disclosed |