SCHEMBL28440910

SCHEMBL28440910

COc1ccc(/C=C/c2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)cc1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.60
CD274 Q9NZQ7 1/20 0.60
CYP1A1 P04798 3/20 0.57
CYP1B1 Q16678 2/20 0.57
TTR P02766 1/20 0.57
NQO2 P16083 1/20 0.57
ABCG2 Q9UNQ0 1/20 0.57
MYC P01106 1/20 0.57
CYP1A2 P05177 2/20 0.57
CYP19A1 P11511 1/20 0.57
GSK3B P49841 1/20 0.57
APP P05067 4/20 0.55
AMY1A P0DUB6 1/20 0.55
LCK P06239 1/20 0.55
PDE4A P27815 1/20 0.53
PDE4B Q07343 1/20 0.53
PDE4C Q08493 1/20 0.53
PDE4D Q08499 1/20 0.53
LMNA P02545 2/20 0.52
KDM4E B2RXH2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28447863 0.97 CYP1A1 (0.62) PDCD1CD274CYP1A1CYP1B1TTR
SCHEMBL28440296 0.95 APP (0.61) CYP1A1CYP1B1TTRNQO2ABCG2
SCHEMBL38661511 0.95 NQO2 (0.66) PDCD1CD274CYP1A1CYP1B1TTR
SCHEMBL17201727 0.94 CYP1A1 (0.67) PDCD1CD274CYP1A1CYP1A2CYP19A1
SCHEMBL17201728 0.94 CYP1A1 (0.67) PDCD1CD274CYP1A1CYP1A2CYP19A1
SCHEMBL9587052 0.92 CYP1A1 (0.65) PDCD1CD274CYP1A1CYP1B1CYP1A2
SCHEMBL9587050 0.92 CYP1A1 (0.65) PDCD1CD274CYP1A1CYP1B1CYP1A2
SCHEMBL13727036 0.90 GSK3B (0.51) PDCD1CD274CYP1A1CYP1B1TTR
SCHEMBL20684252 0.90 PDCD1 (0.50) PDCD1CD274CYP1A1CYP1B1TTR
SCHEMBL17201736 0.90 GSK3B (0.56) PDCD1CD274GSK3BAPPPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106336347-B New method for synthesizing hydroxystilbenes 中国科学院成都有机化学有限公司 2020-08-18 CN disclosed