Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201727 | 1.00 | CYP1A1 (0.67) | CYP1A1CYP1A2CYP19A1PTGS1PTGS2 | |
| SCHEMBL17201738 | 0.95 | CYP1A1 (0.67) | CYP1A1CYP1A2CYP19A1PTGS1PTGS2 | |
| SCHEMBL13725753 | 0.95 | CYP1A1 (0.67) | CYP1A1CYP1A2CYP19A1PTGS1PTGS2 | |
| SCHEMBL28440910 | 0.94 | PDCD1 (0.60) | CYP1A1CYP1A2CYP19A1GSK3BPDCD1 | |
| SCHEMBL28447863 | 0.91 | CYP1A1 (0.62) | CYP1A1CYP1A2CYP19A1GSK3BPDCD1 | |
| SCHEMBL17201748 | 0.90 | APP (0.61) | CYP1A1CYP1A2CYP19A1PTGS1PTGS2 | |
| SCHEMBL17201746 | 0.90 | APP (0.61) | CYP1A1CYP1A2CYP19A1PTGS1PTGS2 | |
| SCHEMBL38661511 | 0.88 | NQO2 (0.66) | CYP1A1CYP1A2GSK3BPDCD1CD274 | |
| SCHEMBL28440296 | 0.88 | APP (0.61) | CYP1A1CYP1A2CYP19A1GSK3BAPP | |
| SCHEMBL9587052 | 0.88 | CYP1A1 (0.65) | CYP1A1CYP1A2GSK3BPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634375-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220380285-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC (US) | 2022-12-01 | — | — | US | disclosed |
| US-11352310-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2020-10-22 | — | — | US | disclosed |
| US-10696615-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2019-06-27 | — | — | US | disclosed |
| US-10196335-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2019-02-05 | — | — | US | disclosed |
| CN-107266297-A | Prenylation hydroxy diphenyl ethylene, the pharmaceutical composition comprising it, purposes and preparation method thereof | 悉尼大学 | 2017-10-20 | — | — | CN | disclosed |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196335-B2 | Prenylated hydroxystilbenes | HMGB2, CYP51A1, CYP8B1 | CYP1A1 525/4885CYP1A2 415/4885CYP19A1 212/4885 |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | CYP1A1 142/4885CYP1A2 146/4885CYP19A1 64/4885 |
| US-20220380285-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | CYP1A1 142/4885CYP1A2 146/4885CYP19A1 64/4885 |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | HMGB2, CYP51A1, CYP8B1 | CYP1A1 525/4885CYP1A2 415/4885CYP19A1 212/4885 |
| US-10696615-B2 | Prenylated hydroxystilbenes | HSD11B1, CYP8B1, NR1H2 | CYP1A1 73/4885CYP1A2 105/4885CYP19A1 79/4885 |
| US-11352310-B2 | Prenylated hydroxystilbenes | HSD11B1, HSD3B1, CYP8B1 | CYP1A1 142/4885CYP1A2 146/4885CYP19A1 64/4885 |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, CYP8B1, NR1H2 | CYP1A1 73/4885CYP1A2 105/4885CYP19A1 79/4885 |
| US-11634375-B2 | Prenylated hydroxystilbenes | HCLS1, IWS1, UTS2R | CYP1A1 1293/4885CYP1A2 1275/4885CYP19A1 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.