Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20622191 | 1.00 | KLK5 (0.41) | KLK5LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL21875826 | 0.89 | ACE (0.45) | ACEAKT1CTSSCTSLCTSB | |
| SCHEMBL21875824 | 0.89 | ACE (0.45) | ACEAKT1CTSSCTSLCTSB | |
| SCHEMBL16119293 | 0.81 | KLK5 (0.44) | KLK5NFKB1NFKB2RELAACE | |
| SCHEMBL6908318 | 0.81 | KLK5 (0.44) | KLK5NFKB1NFKB2RELAACE | |
| SCHEMBL16228157 | 0.81 | KLK5 (0.44) | KLK5NFKB1NFKB2RELAACE | |
| SCHEMBL8909470 | 0.80 | ALDH1A1 (0.46) | KLK5NFKB1NFKB2RELACACNA1B | |
| SCHEMBL6907174 | 0.77 | KLK5 (0.45) | KLK5NFKB1NFKB2RELAACE | |
| SCHEMBL16228121 | 0.77 | KLK5 (0.45) | KLK5NFKB1NFKB2RELAACE | |
| SCHEMBL12091407 | 0.76 | KLK5 (0.43) | KLK5NFKB1NFKB2RELAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134533-B | Phosphorus-containing compound and preparation and application thereof | 维眸生物科技（上海）有限公司 | 2020-08-11 | — | — | CN | disclosed |