Hydrazine

Hydrazine

SCHEMBL28441950

NN.Nc1ccc(C(=O)c2c(O)ccc(C=O)c2O)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
HTT P42858 2/20 0.36
HPGD P15428 1/20 0.36
SNCA P37840 1/20 0.34
IGFBP3 P17936 1/20 0.34
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
MCL1 Q07820 1/20 0.33
TYR P14679 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL28440641 0.76 ERN1 (0.44) ERN1NPC1MAPTRAB9AHTT
Hydrazine SCHEMBL28284209 0.70 ERN1 (0.58) ERN1NPC1RAB9AMEN1KMT2A
SCHEMBL12882137 0.69 ERN1 (0.56) ERN1NPC1RAB9AMEN1KMT2A
SCHEMBL16424352 0.69 HPGD (0.46) CA12CA1CA2CA9CA14
SCHEMBL28059227 0.67 ALDH1A1 (0.56) CA12CA1CA2CA9CA14
SCHEMBL204877 0.67 CA12 (0.59) CA12CA1CA2CA9CA14
SCHEMBL62657 0.67 CA12 (0.59) CA12CA1CA2CA9CA14
SCHEMBL9097535 0.67 CA12 (0.59) CA12CA1CA2CA9CA14
SCHEMBL27894750 0.67 CA12 (0.43) CA12CA1CA2CA9CA14
SCHEMBL1484100 0.67 ERN1 (0.52) ERN1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440089-A Fluorescent material applied to zinc ion content detection and preparation method thereof 西安医学院 2020-07-24 CN disclosed