Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL635835 | 0.82 | CES2 (0.52) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL60741 | 0.78 | — | — | |
| Hydrogen Sulfide SCHEMBL28650892 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4706810 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL31367891 | 0.76 | CES2 (0.62) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL27288630 | 0.76 | — | — | |
| SCHEMBL29126781 | 0.76 | — | — | |
| SCHEMBL27776787 | 0.74 | CES2 (0.60) | CES2CES1ALDH1A1HTTNPSR1 | |
| Oxalic Acid SCHEMBL6090643 | 0.73 | PTPN1 (0.63) | CES2CES1ALDH1A1HTTNPSR1 | |
| Acetic Acid SCHEMBL6883898 | 0.71 | PTGS1 (0.57) | CES2CES1ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419843-B | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of beta-glucuronidase inhibitor | 浙江工业大学 | 2021-07-27 | — | — | CN | claimed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | claimed |
| CN-111419843-A | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of β -glucuronidase inhibitor | 浙江工业大学 | 2020-07-17 | — | — | CN | claimed |
| CN-111419843-B | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of beta-glucuronidase inhibitor | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-111419843-B | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of beta-glucuronidase inhibitor | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-111419843-B | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of beta-glucuronidase inhibitor | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-111419843-A | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of β -glucuronidase inhibitor | 浙江工业大学 | 2020-07-17 | — | — | CN | disclosed |
| CN-111419843-A | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of β -glucuronidase inhibitor | 浙江工业大学 | 2020-07-17 | — | — | CN | disclosed |
| CN-111419843-A | Application of cyanoimine thiazolidine furan carboxamide compound in preparation of β -glucuronidase inhibitor | 浙江工业大学 | 2020-07-17 | — | — | CN | disclosed |