Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 17/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440940 | 0.92 | IDO1 (0.63) | IDO1 | |
| SCHEMBL28435093 | 0.92 | IDO1 (0.50) | IDO1 | |
| SCHEMBL28443050 | 0.92 | IDO1 (0.48) | IDO1F10GPX4 | |
| SCHEMBL28442326 | 0.91 | IDO1 (0.55) | IDO1 | |
| SCHEMBL23647770 | 0.88 | IDO1 (0.47) | IDO1 | |
| SCHEMBL28896935 | 0.85 | IDO1 (0.58) | IDO1 | |
| SCHEMBL23658937 | 0.85 | IDO1 (0.51) | IDO1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28406870 | 0.85 | IDO1 (0.52) | IDO1F10KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL23658938 | 0.84 | IDO1 (0.57) | IDO1 | |
| SCHEMBL28897469 | 0.84 | IDO1 (0.45) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153846-B | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-31 | — | — | CN | claimed |
| CN-111153846-A | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-111153846-B | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-111153846-A | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2020-05-15 | — | — | CN | disclosed |