Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842025 | 0.82 | GID4 (0.36) | GID4L3MBTL1DRD3TAAR1KEAP1 | |
| SCHEMBL3406589 | 0.78 | GID4 (0.57) | GID4L3MBTL1DRD3TAAR1KEAP1 | |
| SCHEMBL1866928 | 0.78 | GID4 (0.57) | GID4L3MBTL1DRD3TAAR1KEAP1 | |
| SCHEMBL3404796 | 0.78 | GID4 (0.57) | GID4L3MBTL1DRD3TAAR1KEAP1 | |
| SCHEMBL1868649 | 0.70 | GID4 (0.53) | GID4L3MBTL1DRD3TAAR1KEAP1 | |
| Hydrochloric Acid SCHEMBL3441725 | 0.69 | GID4 (0.51) | GID4L3MBTL1DRD3TAAR1KEAP1 | |
| SCHEMBL9207161 | 0.69 | TSHR (0.53) | GID4L3MBTL1DRD3KEAP1LMNA | |
| SCHEMBL4864502 | 0.69 | GID4 (0.48) | GID4L3MBTL1DRD3TAAR1LMNA | |
| SCHEMBL18708113 | 0.68 | GID4 (0.32) | GID4TAAR1KEAP1LMNAKMT2A | |
| SCHEMBL12761112 | 0.68 | GID4 (0.50) | GID4L3MBTL1DRD3TAAR1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141168-A1 | HETEROARYL DERIVATIVES | Nippon Shinyaku Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |