Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28442734 | 1.00 | FNTA (0.35) | FNTAFNTBDRD4CXCR4KMT2A | |
| SCHEMBL28435253 | 0.83 | CTSK (0.42) | KMT2ALMNAMEN1 | |
| SCHEMBL16291855 | 0.83 | CTSK (0.42) | KMT2ALMNAMEN1 | |
| SCHEMBL28436878 | 0.81 | DRD4 (0.37) | FNTAFNTBDRD4CXCR4KMT2A | |
| SCHEMBL15639020 | 0.81 | DRD4 (0.37) | FNTAFNTBDRD4CXCR4KMT2A | |
| SCHEMBL16291432 | 0.79 | KDM5B (0.39) | DRD4 | |
| SCHEMBL16310762 | 0.79 | KDM5B (0.39) | DRD4 | |
| SCHEMBL19574692 | 0.72 | KDM5B (0.41) | DRD4 | |
| SCHEMBL27220830 | 0.70 | DRD4 (0.49) | FNTAFNTBDRD4CXCR4KMT2A | |
| Acetic Acid SCHEMBL2943155 | 0.69 | FNTA (0.47) | FNTAFNTBDRD4KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434803-B | Inhibitors of histone demethylases | 吉利德科学公司 | 2020-05-05 | — | — | CN | disclosed |