Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.42 |
| ▸ | KDM5A | P29375 | 5/20 | 0.42 |
| ▸ | KDM5C | P41229 | 5/20 | 0.42 |
| ▸ | NAAA | Q02083 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15639137 | 0.78 | KDM5B (0.66) | KDM5BKDM5AKDM5CNAAAKDM6B | |
| SCHEMBL18708598 | 0.76 | KDM5B (0.54) | KDM5BKDM5AKDM5CNAAAFAAH | |
| SCHEMBL15994210 | 0.66 | KDM5B (0.56) | KDM5BKDM5AKDM5CKDM6BKDM4A | |
| SCHEMBL19676523 | 0.61 | KDM5B (0.55) | KDM5BKDM5AKDM5CKDM6BKDM4A | |
| SCHEMBL29210374 | 0.61 | HPGD (0.57) | NAAAFAAH | |
| SCHEMBL16291579 | 0.59 | KDM5B (0.62) | KDM5BKDM5AKDM5CKDM6BKDM4A | |
| SCHEMBL16291803 | 0.58 | KDM5B (0.67) | KDM5BKDM5AKDM5CKDM6BKDM4A | |
| SCHEMBL15636244 | 0.58 | KDM5B (0.68) | KDM5BKDM5AKDM5CKDM6BKDM4A | |
| SCHEMBL16291681 | 0.58 | KDM5B (0.54) | KDM5BKDM5AKDM5CKDM6BKDM4A | |
| SCHEMBL29210364 | 0.58 | NAAA (0.52) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434803-B | Inhibitors of histone demethylases | 吉利德科学公司 | 2020-05-05 | — | — | CN | disclosed |