Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 19/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438103 | 0.84 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL21682243 | 0.83 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL28439637 | 0.82 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL20721501 | 0.79 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL28438196 | 0.79 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL28441892 | 0.74 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL18205024 | 0.72 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL18205076 | 0.72 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL20475660 | 0.72 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL18571975 | 0.71 | PRMT5 (0.42) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527099-A | Selective inhibitors of protein arginine methyltransferase 5(PRMT5) | 普莱鲁德疗法有限公司 | 2020-08-11 | — | — | CN | disclosed |