Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271587 | 0.91 | TDP1 (0.50) | SMN1; SMN2CYP1A2MAPK10MAPK1CYP19A1 | |
| SCHEMBL28897969 | 0.88 | NPC1 (0.50) | SMN1; SMN2CYP1A2MAPK10MAPK1HPGD | |
| SCHEMBL28450969 | 0.85 | GRM2 (0.54) | SLC9A1GRM2CYP19A1HPGDALDH1A1 | |
| SCHEMBL28443265 | 0.80 | CYP1A2 (0.54) | SMN1; SMN2CYP1A2MAPK10MAPK1CYP19A1 | |
| SCHEMBL12900276 | 0.77 | TDP1 (0.55) | SLC9A1GRM2CYP19A1HPGDHCAR3 | |
| SCHEMBL28451005 | 0.77 | RECQL (0.48) | SMN1; SMN2CYP1A2ALDH1A1TSHRKMT2A | |
| SCHEMBL28440773 | 0.77 | CYP11B1 (0.48) | SMN1; SMN2MAPK10TSHRKMT2AKDM4E | |
| SCHEMBL2014506 | 0.76 | KDM4E (0.43) | SMN1; SMN2CYP1A2SLC9A1ALDH1A1TSHR | |
| SCHEMBL11769430 | 0.75 | CYP1A2 (0.51) | SMN1; SMN2CYP1A2MAPK10MAPK1CYP19A1 | |
| SCHEMBL11767746 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2MAPK1CYP19A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606928-A | Azacyclodiketone compound and preparation method thereof | 维清生物科技(上海)有限公司 | 2020-09-01 | — | — | CN | disclosed |