⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23467140 | 0.96 | — | — | |
| Malonaldehyde SCHEMBL6877197 | 0.78 | — | — | |
| SCHEMBL42541 | 0.71 | — | — | |
| Malonaldehyde SCHEMBL10949336 | 0.71 | ALDH1A1 (0.42) | — | |
| Malonaldehyde SCHEMBL16287 | 0.71 | — | — | |
| Malonaldehyde SCHEMBL4259871 | 0.70 | — | — | |
| SCHEMBL6297993 | 0.69 | — | — | |
| SCHEMBL258859 | 0.69 | — | — | |
| SCHEMBL490428 | 0.69 | — | — | |
| Malonaldehyde SCHEMBL8182493 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958928-A1 | ESTRA-1,3,5(10),16-TETRAENE-3-CARBOXAMIDES FOR INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASE (AKR1 C3) | Bayer Pharma Aktiengesellschaft (DE) | 2015-12-30 | — | — | EP | claimed |
| EP-2776407-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2014-09-17 | — | — | EP | claimed |
| WO-2014128108-A1 | ESTRA-1,3,5(10),16-TETRAENE-3-CARBOXAMIDES FOR INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASE (AKR1 C3) | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-08-28 | — | — | WO | claimed |
| EP-2678334-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2014-01-01 | — | — | EP | claimed |
| WO-2013070657-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| CN-103080108-A | Pyridyl-amine fused azadecalin modulators | CORCEPT THERAPEUTICS INC | 2013-05-01 | — | — | CN | claimed |
| CN-102918027-A | Modulators of the gpr119 receptor and the treatment of disorders related thereto | ARENA PHARM INC | 2013-02-06 | — | — | CN | claimed |
| CN-102725290-A | Fused heterocyclic compounds as ion channel modulators | GILEAD PALO ALTO INC | 2012-10-10 | — | — | CN | claimed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | claimed |
| CN-1211385-C | Bicyclic imidazo-5-yl-amine derivs. | GRUENENTHAL GMBH (DE) | 2005-07-20 | — | — | CN | claimed |
| CN-118354759-A | Compositions comprising 2' -deoxycytidine analogs and their use for treating sickle cell disease, thalassemia and cancer | 阿基拉比奥有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20240216372-A1 | THERAPEUTICS FOR KELOIDS AND OTHER FIBROTIC DISORDERS | NATIONAL INSTITUTES OF HEALTH | 2024-07-04 | — | — | US | disclosed |
| US-20240207359-A1 | INHIBITION OF BETA-ARRESTIN OLIGOMERIZATION IN TAUOPATHY | UNIVERSITY OF SOUTH FLORIDA | 2024-06-27 | — | — | US | disclosed |
| EP-4387626-A1 | ALLOPREGNANOLONE ANALOGUES FOR HIV VIREMIA AND NEUROTOXICITY PROTECTION | University of Mississippi (US) | 2024-06-26 | — | — | EP | disclosed |
| EP-3793562-B1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE | OHIO STATE INNOVATION FOUNDATION (US) | 2024-06-19 | — | — | EP | disclosed |
| EP-0242767-A2 | N-dihydroindolyl ethyl-sulfon amides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| US-4528352-A | RTV silicon compositions and processes | GENERAL ELECTRIC COMPANY (US) | 1985-07-09 | — | — | US | disclosed |
| US-4288374-A | MULTISTAGE FROM PROPYLENE AND FORMALDEHYDE USING ALCOHOL STABILIZED SILICA SAND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| US-4261901-A | Synthesis of tetrahydrofuran | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4249938-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |