Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 5/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14776468 | 0.94 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL8470093 | 0.94 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| Phosphoric Acid SCHEMBL28448051 | 0.87 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4GPR84 | |
| SCHEMBL21694364 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL21694381 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL23581478 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL21694377 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL23581501 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL19456772 | 0.84 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4FFAR4 | |
| SCHEMBL23581497 | 0.83 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250347-B | Salt-fog-resistant phosphate modified acrylic core-shell emulsion | 吉力水性新材料科技（珠海）有限公司 | 2020-07-21 | — | — | CN | disclosed |