Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 17/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28457076 | 0.91 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL28453811 | 0.89 | GLS (0.60) | GLS | |
| SCHEMBL28457461 | 0.88 | GLS (0.75) | GLSKCNH2 | |
| SCHEMBL18358030 | 0.87 | GLS (0.60) | GLSKCNH2 | |
| SCHEMBL16880268 | 0.84 | GLS (0.55) | GLS | |
| SCHEMBL30369307 | 0.83 | GLS (0.57) | GLS | |
| SCHEMBL22006503 | 0.82 | KCNH2 (0.80) | GLSKCNH2 | |
| SCHEMBL16880212 | 0.82 | GLS (0.73) | GLS | |
| SCHEMBL30369226 | 0.82 | GLS (0.73) | GLS | |
| SCHEMBL16880177 | 0.82 | GLS (0.73) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503570-B | Pharmaceutical composition containing sorafenib and application thereof | 诺言医药科技(上海)有限公司 | 2020-08-25 | — | — | CN | disclosed |