SCHEMBL2844545

SCHEMBL2844545

Cc1ccc(C(C)c2ccccc2)cc1C(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.46
RXRA P19793 1/20 0.38
ACP3 P15309 1/20 0.37
ESR1 P03372 1/20 0.37
PDCD1 Q15116 1/20 0.37
ESR2 Q92731 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
LMNA P02545 2/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2C P18825 1/20 0.36
HIF1A Q16665 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
DAO P14920 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29486495 0.84 TYR (0.46) TYRACP3ESR1LMNAGAA
SCHEMBL444327 0.84 TYR (0.46) TYRACP3ESR1LMNAGAA
SCHEMBL29486483 0.83 TYR (0.40) TYRESR1PDCD1ESR2CD274
SCHEMBL441363 0.83 TYR (0.40) TYRESR1PDCD1ESR2CD274
SCHEMBL14452298 0.81 ALDH1A1 (0.43) TYRACP3LMNAKDM4ETSHR
SCHEMBL27048577 0.79 TYR (0.48) TYRESR1PDCD1ESR2CD274
SCHEMBL710709 0.79 ACP3 (0.50) TYRACP3ESR1LMNAADRA2A
SCHEMBL9064122 0.79 TYR (0.52) TYRRXRAACP3LMNAADRA2A
SCHEMBL29638766 0.79 ACP3 (0.50) TYRACP3ESR1LMNAADRA2A
SCHEMBL28666265 0.79 ACP3 (0.50) TYRACP3ESR1LMNAADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190233684-A1 WATERBORNE BONDING ADHESIVE FORMULATION FOR SHEET MEMBRANE INCORPORATING A SOLID PLASTICIZER AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2019-08-01 US claimed
US-6908673-B2 Cable with recyclable covering PIRELLI CAVI E SISTEMI S.P.A. (IT) 2005-06-21 US claimed
EP-1295301-B1 CABLE WITH RECYCLABLE COVERING PIRELLI & C SPA (IT) 2004-04-14 EP claimed
US-20030138628-A1 Cable with recyclable covering PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2003-07-24 US claimed
EP-1295301-A1 CABLE WITH RECYCLABLE COVERING PIRELLI S.p.A. (IT) 2003-03-26 EP claimed
WO-2002003398-A1 CABLE WITH RECYCLABLE COVERING PIRELLI CAVI E SISTEMI SPA (IT) 2002-01-10 WO claimed
US-4785043-A THERMOPLASTIC ELASTOMERS, MIXTURES, SOFTENERS NIPPON OIL CO., LTD. (JP) 1988-11-15 US claimed
US-4329529-A Traction fluids for traction drive transmissions NIPPON OIL CO., LTD. (JP) 1982-05-11 US claimed
US-4145338-A AROMATIC HYDROCARBONS NIPPON OIL CO., LTD. (JP) 1979-03-20 US claimed
US-11111420-B2 Waterborne bonding adhesive formulation for sheet membrane incorporating a solid plasticizer ILLINOIS TOOL WORKS INC. (US) 2021-09-07 US disclosed
US-20190233684-A1 WATERBORNE BONDING ADHESIVE FORMULATION FOR SHEET MEMBRANE INCORPORATING A SOLID PLASTICIZER AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2019-08-01 US disclosed
EP-1682324-B1 METHOD AND PLANT FOR THE INTRODUCTION OF A LIQUID INTO A MOLTEN MASS UNDER PRESSURE PRYSMIAN SPA (IT) 2016-08-10 EP disclosed
US-7807091-B2 Method and plant for the introduction of a liquid into a molten mass under pressure PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2010-10-05 US disclosed
US-7744950-B2 Extruding a thermoplastic material containing dielectric liquid; passing thermoplastic material through static mixer; depositing and shaping said thermoplastic material around a conductor so as to obtain a layer of thermoplastic coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2010-06-29 US disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed
US-4331683-A SENSITIZATION, ANTIALLERGENS PFIZER INC. (US) 1982-05-25 US disclosed
US-4329529-A Traction fluids for traction drive transmissions NIPPON OIL CO., LTD. (JP) 1982-05-11 US disclosed
US-4296129-A ANTIAASTHMATIC INHIBITOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS PFIZER, INC. (US) 1981-10-20 US disclosed
US-4145338-A AROMATIC HYDROCARBONS NIPPON OIL CO., LTD. (JP) 1979-03-20 US disclosed
JP-S05540726-A 0001-01-01 JP disclosed