SCHEMBL2844549

SCHEMBL2844549

Cc1cccc(C(C)c2ccccc2)c1C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.42
ACP3 P15309 1/20 0.41
ESR1 P03372 1/20 0.38
SCN4A P35499 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2D6 P10635 2/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
ADRA2B P18089 1/20 0.36
CHRM3 P20309 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
HRH2 P25021 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548094 0.90 TYR (0.41) TYRACP3ESR1SCN4AL3MBTL1
SCHEMBL3088422 0.87 TSHR (0.41) TYRACP3SCN4AL3MBTL1CYP2D6
SCHEMBL29358402 0.83 ADRA2A (0.47) TYRACP3ESR1SCN4AL3MBTL1
SCHEMBL115911 0.83 ADRA2A (0.47) TYRACP3ESR1SCN4AL3MBTL1
SCHEMBL710709 0.83 ACP3 (0.50) TYRACP3ESR1CYP2D6SLC22A2
SCHEMBL29638766 0.83 ACP3 (0.50) TYRACP3ESR1CYP2D6SLC22A2
SCHEMBL28666265 0.83 ACP3 (0.50) TYRACP3ESR1CYP2D6SLC22A2
SCHEMBL10599634 0.82 TYR (0.43) TYRSLC6A2HTR2CHTR2BCYP3A4
SCHEMBL4156669 0.81 TYR (0.48) TYRACP3CYP2D6ADRA2ASLC6A2
SCHEMBL5605956 0.80 ADRA2A (0.45) TYRACP3ESR1SCN4AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6908673-B2 Cable with recyclable covering PIRELLI CAVI E SISTEMI S.P.A. (IT) 2005-06-21 US claimed
EP-1295301-B1 CABLE WITH RECYCLABLE COVERING PIRELLI & C SPA (IT) 2004-04-14 EP claimed
US-20030138628-A1 Cable with recyclable covering PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2003-07-24 US claimed
EP-1295301-A1 CABLE WITH RECYCLABLE COVERING PIRELLI S.p.A. (IT) 2003-03-26 EP claimed
WO-2002003398-A1 CABLE WITH RECYCLABLE COVERING PIRELLI CAVI E SISTEMI SPA (IT) 2002-01-10 WO claimed
US-4785043-A THERMOPLASTIC ELASTOMERS, MIXTURES, SOFTENERS NIPPON OIL CO., LTD. (JP) 1988-11-15 US claimed
JP-55040726-A None JP disclosed
EP-1682324-B1 METHOD AND PLANT FOR THE INTRODUCTION OF A LIQUID INTO A MOLTEN MASS UNDER PRESSURE PRYSMIAN SPA (IT) 2016-08-10 EP disclosed
US-7807091-B2 Method and plant for the introduction of a liquid into a molten mass under pressure PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2010-10-05 US disclosed
US-7744950-B2 Extruding a thermoplastic material containing dielectric liquid; passing thermoplastic material through static mixer; depositing and shaping said thermoplastic material around a conductor so as to obtain a layer of thermoplastic coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2010-06-29 US disclosed
EP-1342249-B1 PROCESS FOR PRODUCING A CABLE WITH A RECYCLABLE COATING PRYSMIAN SPA (IT) 2009-01-07 EP disclosed
US-20070248748-A1 Method and Plant for the Introduction of a Liquid Into a Molten Mass Under Pressure PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2007-10-25 US disclosed
EP-1682324-A1 METHOD AND PLANT FOR THE INTRODUCTION OF A LIQUID INTO A MOLTEN MASS UNDER PRESSURE Prysmian Cavi e Sistemi Energia S.r.l. (IT) 2006-07-26 EP disclosed
EP-0500435-A1 Use of isomers of mono- and bis(methylbenzyle)xylene as heat-transfer fluid ELF ATOCHEM S.A. (FR) 1992-08-26 EP disclosed
EP-0176366-B1 IMPREGNATED CAPACITOR NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
US-4785043-A THERMOPLASTIC ELASTOMERS, MIXTURES, SOFTENERS NIPPON OIL CO., LTD. (JP) 1988-11-15 US disclosed
US-4631632-A METALLIZED POLYPROPYLENE FILM IMPREGNATED WITH DIELECTRIC HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-12-23 US disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed
JP-S5540726-A FLUID FOR TRACTION DRIVE NIPPON OIL CO LTD 1980-03-22 JP disclosed
JP-S05540726-A 0001-01-01 JP disclosed