Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 15/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468518 | 0.76 | DHODH (1.00) | DHODH | |
| SCHEMBL2848357 | 0.71 | DHODH (0.62) | DHODH | |
| SCHEMBL3670177 | 0.69 | DHODH (0.82) | DHODH | |
| SCHEMBL1016143 | 0.66 | KMT2A (0.58) | DHODHKMT2AMEN1CNR1 | |
| SCHEMBL27516459 | 0.66 | TTR (0.59) | DHODHKMT2AMEN1FABP3FABP4 | |
| SCHEMBL468472 | 0.65 | DHODH (1.00) | DHODHFABP3FABP4 | |
| SCHEMBL10783212 | 0.65 | KMT2A (0.50) | DHODHKMT2AMEN1CNR1 | |
| Sulfuric Acid SCHEMBL4111782 | 0.65 | DHODH (0.47) | DHODHKMT2AMEN1CNR1 | |
| SCHEMBL28046722 | 0.64 | KMT2A (0.52) | DHODHKMT2AMEN1CNR1 | |
| SCHEMBL9907739 | 0.64 | HTR5A (0.53) | DHODHKMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |