Phthalic Acid

Phthalic Acid

SCHEMBL28446205

O=C(O)c1ccccc1C(=O)O.OCC(O)C(O)CO

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
ALOX15 P16050 1/20 0.64
MAPT P10636 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
AKR1C3 P42330 1/20 0.50
KDM4E B2RXH2 3/20 0.49
TAAR1 Q96RJ0 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
HPGD P15428 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL11508889 0.91 ALDH1A1 (0.58) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28438466 0.91 ALDH1A1 (0.58) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL11511047 0.91 ALDH1A1 (0.58) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28441202 0.91 ALDH1A1 (0.58) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Salicylic Acid SCHEMBL28438472 0.88 ALDH1A1 (0.69) ALDH1A1ALOX15MAPTHDAC8KDM4E
Phthalic Acid SCHEMBL28858619 0.86 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL9417364 0.86 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL120455 0.86 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL10937971 0.84 ALDH1A1 (0.61) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28184672 0.84 ALDH1A1 (0.61) ALDH1A1ALOX15MAPTHDAC8AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631779-B Polyol esters and their use in processing halogenated vinyl polymers 济南金昌树新材料科技有限公司 2020-07-14 CN disclosed