Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448820 | 0.94 | GAA (0.35) | GAANPSR1KMT2AMEN1KDM4E | |
| SCHEMBL28442795 | 0.93 | DPP4 (0.35) | GAAKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28453316 | 0.85 | SLC22A12 (0.38) | GAANPSR1KMT2AMEN1KDM4E | |
| SCHEMBL28448524 | 0.81 | GAA (0.34) | GAAKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28442805 | 0.79 | SLC22A12 (0.35) | GAAKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28443600 | 0.78 | KDM4E (0.32) | GAAKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28450315 | 0.78 | DPP4 (0.35) | GAAKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28446607 | 0.76 | MEN1 (0.33) | GAAKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28447349 | 0.75 | GAA (0.36) | GAANPSR1KMT2AMEN1KDM4E | |
| SCHEMBL28448821 | 0.74 | AKR1C3 (0.35) | GAAKMT2AMEN1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689928-B | Quinoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-05-26 | — | — | CN | claimed |