Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450315 | 0.96 | DPP4 (0.35) | SLC22A12GAAMEN1KMT2ADPP4 | |
| SCHEMBL28453316 | 0.94 | SLC22A12 (0.38) | SLC22A12GAAMEN1KMT2APTGDR2 | |
| SCHEMBL28448820 | 0.85 | GAA (0.35) | GAAMEN1KMT2ADPP4KDM4E | |
| SCHEMBL28442795 | 0.82 | DPP4 (0.35) | GAAMEN1KMT2ADPP4KDM4E | |
| SCHEMBL28448832 | 0.80 | GAA (0.34) | GAAMEN1KMT2APTGDR2KDM4E | |
| SCHEMBL28451078 | 0.80 | GAA (0.34) | SLC22A12GAAMEN1KMT2APTGDR2 | |
| SCHEMBL28447347 | 0.79 | GAA (0.36) | GAAMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL28897440 | 0.77 | ALDH1A1 (0.33) | GAAMEN1KMT2APTGDR2KDM4E | |
| SCHEMBL28444756 | 0.74 | MAPT (0.34) | GAAMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL28444818 | 0.74 | MEN1 (0.33) | GAAMEN1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689928-B | Quinoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-108689928-B | Quinoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-05-26 | — | — | CN | disclosed |