Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.69 |
| ▸ | BRD4 | O60885 | 7/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500871 | 0.86 | EPHX2 (0.67) | EPHX2MAPK10DRD2KDM1AMAOB | |
| SCHEMBL28451186 | 0.84 | EPHX2 (0.49) | EPHX2BRD4CREBBPDRD2KDM1A | |
| SCHEMBL29500912 | 0.84 | EPHX2 (0.49) | EPHX2BRD4CREBBPDRD2KDM1A | |
| SCHEMBL173219 | 0.83 | EPHX2 (0.69) | EPHX2DRD2KDM1AMAOBKMT2A | |
| SCHEMBL31694392 | 0.83 | EPHX2 (0.69) | EPHX2DRD2KDM1AMAOBKMT2A | |
| SCHEMBL28454474 | 0.83 | EPHX2 (0.48) | EPHX2BRD4CREBBPDRD2KMT2A | |
| SCHEMBL29500783 | 0.83 | EPHX2 (0.48) | EPHX2BRD4CREBBPDRD2KMT2A | |
| SCHEMBL29500902 | 0.83 | EPHX2 (0.48) | EPHX2BRD4CREBBPKDM1AMAOB | |
| SCHEMBL29500985 | 0.83 | EPHX2 (0.48) | EPHX2BRD4CREBBPKDM1AMAOB | |
| SCHEMBL28451195 | 0.83 | EPHX2 (0.48) | EPHX2BRD4CREBBPKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479813-B | Triazolobenzazepines as vasopressin V1A receptor antagonists | 吉瑞工厂 | 2023-03-21 | — | — | CN | disclosed |
| EP-3724192-B1 | TRIAZOLOBENZAZEPINES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2022-08-03 | — | — | EP | disclosed |
| US-11298363-B2 | Triazolobenzazepines as vasopressin V1a receptor antagonists | RICHTER GEDEON NYRT. (HU) | 2022-04-12 | — | — | US | disclosed |
| CN-111479813-A | Triazolobenzazepines as vasopressin V1A receptor antagonists | 吉瑞工厂 | 2020-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11298363-B2 | Triazolobenzazepines as vasopressin V1a receptor antagonists | AVPR1B, AVPR1A, AVPR2 | EPHX2 2042/4885BRD4 1235/4885CREBBP 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.