Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.69 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694392 | 1.00 | EPHX2 (0.69) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL29565539 | 0.89 | MTNR1A (0.66) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL3682479 | 0.89 | MTNR1A (0.66) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL1015075 | 0.88 | KDM1A (0.63) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL1015074 | 0.88 | KDM1A (0.63) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL1015676 | 0.88 | KDM1A (0.63) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL29675257 | 0.85 | EPHX2 (0.68) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL22527375 | 0.85 | EPHX2 (0.68) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL28681707 | 0.85 | EPHX2 (0.68) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL6502466 | 0.84 | MEN1 (0.55) | EPHX2KMT2AGRM7MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114940700-A | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114349820-A | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-108290926-B | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-02-08 | — | — | CN | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-9439436-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| WO-2012030986-A2 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012006276-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012006276-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011162562-A2 | [6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-12-29 | — | — | WO | disclosed |
| CN-102056894-A | Homocysteine synthase inhibitor | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101151245-A | Indan-amide derivatives with glycogen phosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | CN | disclosed |
| CN-101151267-A | Chemical compounds | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | EPHX2 3148/4885KDM1A 65/4885MAOB 683/4885 |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | PGLS, BLVRB, AADAC | EPHX2 2216/4885KDM1A 30/4885MAOB 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.