Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.74 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.62 |
| ▸ | MST1R | Q04912 | 1/20 | 0.62 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447978 | 1.00 | EGFR (0.74) | EGFRERBB2RETMST1RERBB4 | |
| SCHEMBL28444356 | 0.96 | EGFR (0.80) | EGFR | |
| SCHEMBL28444354 | 0.96 | EGFR (0.80) | EGFR | |
| SCHEMBL28452004 | 0.92 | EGFR (0.79) | EGFR | |
| SCHEMBL28452005 | 0.92 | EGFR (0.79) | EGFR | |
| SCHEMBL17940128 | 0.91 | EGFR (0.79) | EGFRERBB2RETMST1RERBB4 | |
| SCHEMBL17940133 | 0.91 | EGFR (0.79) | EGFRERBB2RETMST1RERBB4 | |
| SCHEMBL17940131 | 0.91 | EGFR (0.79) | EGFRERBB2RETMST1RERBB4 | |
| SCHEMBL17940077 | 0.89 | EGFR (0.92) | EGFR | |
| SCHEMBL17940078 | 0.89 | EGFR (0.92) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556295-B | Quinazoline derivatives and process for their preparation | 正大天晴药业集团股份有限公司 | 2020-09-04 | — | — | CN | disclosed |