Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452004 | 1.00 | EGFR (0.79) | EGFR | |
| SCHEMBL28444354 | 0.96 | EGFR (0.80) | EGFR | |
| SCHEMBL28444356 | 0.96 | EGFR (0.80) | EGFR | |
| SCHEMBL28447978 | 0.92 | EGFR (0.74) | EGFR | |
| SCHEMBL28447976 | 0.92 | EGFR (0.74) | EGFR | |
| SCHEMBL17940147 | 0.90 | EGFR (0.85) | EGFR | |
| SCHEMBL17940140 | 0.90 | EGFR (0.85) | EGFR | |
| SCHEMBL17940073 | 0.89 | EGFR (1.00) | EGFR | |
| SCHEMBL16605759 | 0.89 | EGFR (1.00) | EGFR | |
| SCHEMBL17940107 | 0.88 | EGFR (0.86) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556295-B | Quinazoline derivatives and process for their preparation | 正大天晴药业集团股份有限公司 | 2020-09-04 | — | — | CN | disclosed |