Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 15/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849386 | 1.00 | MAOA (0.38) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL2841906 | 1.00 | MAOA (0.38) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL2841087 | 1.00 | MAOA (0.38) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL2842877 | 1.00 | MAOA (0.38) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL2844861 | 1.00 | MAOA (0.38) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL2842826 | 1.00 | MAOA (0.38) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL3062421 | 0.94 | HDAC3 (0.32) | MAOACYP3A4CYP2D6 | |
| SCHEMBL3062417 | 0.94 | HDAC3 (0.32) | MAOACYP3A4CYP2D6 | |
| SCHEMBL2847637 | 0.94 | MAOA (0.39) | MAOACYP3A4CYP2D6MAOBCYP2C9 | |
| SCHEMBL2845413 | 0.93 | HDAC3 (0.32) | MAOACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256120-A1 | Oxazolidinone-quinolone hybrids as antibacterial compounds | Actelion Pharmaceuticals Ltd. (CH) | 2010-12-01 | — | — | EP | disclosed |