SCHEMBL28448277

SCHEMBL28448277

Cc1cc(C)cc(P(Br)C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
C1S P09871 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11318825 0.72 ALDH1A1 (0.38) ALDH1A1TSHRPRSS1PRSS2C1S
SCHEMBL14653011 0.72 ALDH1A1 (0.38) ALDH1A1TSHRPRSS1PRSS2C1S
SCHEMBL11904888 0.71 ALDH1A1 (0.42) ALDH1A1TSHRPRSS1PRSS2C1S
Bromide SCHEMBL29193903 0.70 ALDH1A1 (0.36) ALDH1A1TSHRPRSS1PRSS2C1S
SCHEMBL28897210 0.69 ALDH1A1 (0.40) ALDH1A1TSHRPRSS1PRSS2C1S
SCHEMBL25226060 0.68 TDP1 (0.41) ALDH1A1TSHR
SCHEMBL25219985 0.68 ALDH1A1 (0.35) ALDH1A1TSHRPRSS1PRSS2C1S
SCHEMBL12584883 0.67 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL1223821 0.67 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL341533 0.65 ALDH1A1 (0.67) ALDH1A1TSHRPRSS1PRSS2C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN disclosed