Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.77 |
| ▸ | HTR2B | P41595 | 1/20 | 0.77 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820594 | 0.92 | NPC1 (0.86) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| 2-Acetylaminofluorene SCHEMBL21114365 | 0.87 | CYP1A2 (1.00) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| 2-Acetylaminofluorene SCHEMBL29364009 | 0.87 | CYP1A2 (1.00) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| 2-Acetylaminofluorene SCHEMBL29829339 | 0.87 | CYP1A2 (1.00) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| 2-Acetylaminofluorene SCHEMBL75140 | 0.87 | CYP1A2 (1.00) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| 2-Acetylaminofluorene SCHEMBL6903872 | 0.86 | CYP1A2 (0.97) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| SCHEMBL1091777 | 0.82 | BAZ2B (0.82) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| SCHEMBL7476518 | 0.82 | NPC1 (0.69) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| 2-Acetylaminofluorene SCHEMBL5663545 | 0.82 | CYP1A2 (0.89) | NPC1RAB9AMAOACYP1A2ADRA2A | |
| SCHEMBL2962505 | 0.81 | MAOA (0.84) | NPC1RAB9AMAOACYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440746-B | Ericerus pela capable of inhibiting fusarium pathogenic bacteria and application thereof | 甘肃省科学院生物研究所 | 2021-02-19 | — | — | CN | disclosed |
| CN-111440746-A | Ericerus pela capable of inhibiting fusarium pathogenic bacteria and application thereof | 甘肃省科学院生物研究所 | 2020-07-24 | — | — | CN | disclosed |