Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TTPA | P49638 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 5/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | PHLPP1 | O60346 | 2/20 | 0.34 |
| ▸ | ILK | Q13418 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444734 | 0.84 | PSEN1 (0.43) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL28454235 | 0.84 | PSEN1 (0.43) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL28454237 | 0.84 | PSEN1 (0.43) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL28444736 | 0.84 | PSEN1 (0.43) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL9285268 | 0.83 | LMNA (0.55) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL21929589 | 0.83 | LMNA (0.55) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL21931412 | 0.83 | LMNA (0.55) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL21929591 | 0.83 | LMNA (0.55) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL21931411 | 0.83 | LMNA (0.55) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL21131789 | 0.83 | LMNA (0.55) | LMNATTPAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473567-B | Formation of chromanes and chromenes by using silver (I) or gold (I) salts or complexes | 帝斯曼知识产权资产管理有限公司 | 2020-07-31 | — | — | CN | disclosed |