Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448563 | 0.82 | EGFR (0.47) | EGFRIGF1RKCNH2 | |
| SCHEMBL29855954 | 0.69 | EGFR (0.54) | EGFR | |
| SCHEMBL17196895 | 0.68 | EGFR (0.54) | EGFRKCNH2 | |
| SCHEMBL30041502 | 0.68 | EGFR (0.51) | EGFRKCNH2 | |
| SCHEMBL28455448 | 0.67 | ALK (0.46) | EGFRIGF1RKCNH2 | |
| SCHEMBL17196818 | 0.67 | EGFR (0.51) | EGFRKCNH2 | |
| SCHEMBL17059196 | 0.67 | EGFR (0.52) | EGFRKCNH2 | |
| SCHEMBL17059199 | 0.66 | EGFR (0.52) | EGFRKCNH2 | |
| SCHEMBL14719389 | 0.65 | EGFR (0.72) | EGFRIGF1RKCNH2 | |
| SCHEMBL17059355 | 0.65 | EGFR (0.69) | EGFRIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384694-B | Substituted aminopyrimidine derivative and preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-09-04 | — | — | CN | disclosed |