Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CRHBP | P24387 | 2/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203805 | 0.91 | HDAC6 (0.70) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL30642693 | 0.90 | MEN1 (0.69) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL10018575 | 0.90 | MEN1 (0.69) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL19886991 | 0.87 | MEN1 (0.69) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL20936540 | 0.86 | MEN1 (0.71) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL19886992 | 0.86 | MEN1 (0.71) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL7732734 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28198224 | 0.82 | MEN1 (0.86) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12696861 | 0.82 | HDAC3 (0.62) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12696859 | 0.82 | HDAC3 (0.80) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698648-B | Naphthylimide derivative containing cholesterol and synthesis and application thereof | 大连理工大学 | 2020-08-14 | — | — | CN | disclosed |
| CN-107698648-A | Naphthylimide derivative containing cholesterol and synthesis and application thereof | 大连理工大学 | 2018-02-16 | — | — | CN | disclosed |