Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.70 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | CRHBP | P24387 | 4/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696859 | 0.91 | HDAC3 (0.80) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL28448606 | 0.91 | MEN1 (0.73) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12660521 | 0.88 | MEN1 (0.64) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL22699960 | 0.87 | MEN1 (0.80) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL28198225 | 0.85 | HDAC6 (0.71) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL28197565 | 0.85 | HDAC6 (0.64) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12660392 | 0.84 | HDAC6 (0.69) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL28544782 | 0.83 | HDAC6 (0.81) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12660395 | 0.83 | MEN1 (0.67) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12660394 | 0.83 | HDAC6 (0.65) | HDAC6HDAC3HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698648-B | Naphthylimide derivative containing cholesterol and synthesis and application thereof | 大连理工大学 | 2020-08-14 | — | — | CN | disclosed |
| CN-107698648-A | Naphthylimide derivative containing cholesterol and synthesis and application thereof | 大连理工大学 | 2018-02-16 | — | — | CN | disclosed |