Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20892799 | 0.84 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL20892818 | 0.84 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL16584963 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL8765444 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL8766092 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL10875526 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL7632691 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL8966072 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL36597 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH | |
| SCHEMBL13224427 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108424762-B | Self-suspending proppant for hydraulic fracturing and preparation method thereof | 天津新翔油气技术有限公司 | 2020-08-21 | — | — | CN | disclosed |