Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219027 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL18246525 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL30134669 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL18246450 | 1.00 | APLNR (1.00) | APLNR | |
| SCHEMBL21097425 | 0.95 | APLNR (1.00) | APLNR | |
| SCHEMBL18247063 | 0.95 | APLNR (1.00) | APLNR | |
| SCHEMBL18246756 | 0.93 | APLNR (1.00) | APLNR | |
| SCHEMBL28458470 | 0.93 | APLNR (1.00) | APLNR | |
| SCHEMBL21748122 | 0.92 | APLNR (1.00) | APLNR | |
| SCHEMBL20549252 | 0.92 | APLNR (1.00) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137545-B | Triazole agonists of the APJ receptor | 美国安进公司 | 2020-09-22 | — | — | CN | claimed |
| EP-4532015-A1 | APELIN RECEPTOR MODULATORS FOR TREATMENT OF A DISORDER OR DISEASE ASSOCIATED WITH BBB PERMEABILITY | Bioage Labs, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-117897157-A | Apelin receptor modulators for the treatment of age-related muscle disorders | 百爱及生物医药公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023235360-A1 | APELIN RECEPTOR MODULATORS FOR TREATMENT OF A DISORDER OR DISEASE ASSOCIATED WITH BBB PERMEABILITY | BioAge Labs, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |
| CN-108137545-B | Triazole agonists of the APJ receptor | 美国安进公司 | 2020-09-22 | — | — | CN | disclosed |